Belma Konuklugil, Bülent Gözcelioglu and Peter Proksch
Ankara University, Faculty of Pharmacy, Department of Pharmacognosy, 06100, Tandogan, Ankara Türkey
Endosymbiotic fungus Hypocrea lixii associated with the marine sponge Axinella polypoides, Penicillium concentricum associated with marine sponge Ircinia oros and Chaetomium globosum associated with Sarcotragus spinulosa were isolated and identified by morfological criteria and phylogenetic analyses based on internal transcribed spacer (ITS) regions. This paper deals with isolation of ferulic acid from marine associated fungi Hypocrea lixii, chaetochromin A from marine associated fungi Penicillium concentricum and chaetomin from Chaetomium globosum. Their structures were determined by comprehensive analyses of 1H and 13C NMRs and LS/MS mass spectrometric datas. Preliminary studies showed that this is the first report of ferulic acid to be isolated from marine sponge Axinella polypoides associated fungi Hypocrea lixii. In addition to that, there is no report showed chaetochromin A was isolated from marine fungi Penicillium concentricum