Om Prakash Yadav
Chemistry and Bio-Chemistry, CCS Haryana Agricultural University, India
In the recent years, due to the development of new strains, resistance of bacteria to the commonly used antibiotics drug has increased. Most of the Antibiotics being used, today, are of organic nature. Some of these are extremely irritant and even toxic, therefore, there is much interest in finding ways to formulate new types of safe and cost-effective biocidal materials. Nanosize inorganic material such as metals and their salts during their antibiotic action, can cause denaturation of proteins present in bacterial cell walls. This paper will highlight the synthesis, characterization and antimicrobial activity of as-synthesized inorganic antibiotics against gram positive (Staphylococcus aureus and Streptococcus) as well as gram negative (Pseudomonas aeruginosa and Escherichia coli) bacteria using paper disc diffusion technique. Effects of doping silver and Sulphur in ZnS nanoparticles on their antimicrobial activity will be reported and discussed. The antimicrobial performance of assynthesized nanomaterial will be compared with the commonly used antibiotic drugs.
Keywords: Antibiotics, inorganic, Escherichia coli, nanomaterial, Streptococcus.